Our Expertise in Medicinal Chemistry
Accelerating drug discovery with high-quality compounds and flexible business models.
Medicinal Chemistry
At Alentris Synthesis, our medicinal chemistry contract research services feature a dedicated team of scientists collaborating with industry leaders and computational chemistry experts. We cater to mg-to-kg scale chemistry requirements, offering innovative and efficient solutions.
Our team excels in developing methodologies, including single-step, multi-step synthesis, small arrays, and focused libraries designed for hit-to-lead and lead optimization projects.
Medicinal chemistry projects at Alentris Synthesis involve proposing Structure Activity Relationship (SAR) ideas based on the target of interest and prior scaffold iterations. Upon agreeing on the scientific approach, we synthesize compounds for optimization, advancing them to candidate selection.
All compound deliveries are accompanied by comprehensive characterization data, including high-field NMR and purity/mass analysis via LC-MS, HPLC, or GC. Additionally, our Supercritical Fluid Chromatography enables precise chiral separations, enhancing throughput and efficiency.
Our Key Services
Over the years, SynSmarts’ team of medicinal chemists have helped multiple programs from early discovery to clinical stage across oncology, metabolic disorders, and other therapeutic areas.
Hit, Lead, Candidate
Focused Library Generation
Building Blocks
Impurities / Metabolites
Specialized Chemistry Capabilities
Our expertise spans diverse areas of advanced chemistry
Other Service
Custom Synthesis Services
At Alentris Synthesis, we offer end-to-end custom synthesis solutions under a "Fee for Service" (FFS) business model, leveraging advanced scientific expertise and infrastructure. Our team specializes in synthesizing complex molecules, tackling even the most challenging chemistry with innovative approaches tailored to client needs.
Discovery Chemistry
At Alentris Synthesis, we lead the way in drug discovery chemistry services, leveraging the exceptional expertise of our scientists and state-of-the-art infrastructure. Our team of drug discovery chemists possesses extensive experience, particularly in multi-step organic synthesis across diverse therapeutic
Synthetic Chemistry
Alentris Synthesis offers a broad spectrum of synthetic chemistry services aimed at accelerating the drug discovery process for biotech and pharmaceutical innovators worldwide. With a team of skilled scientists proficient in tackling complex synthetic routes, we specialize in synthesizing high-quality compounds with rapid speed. We work on early-stage discovery projects, producing intermediates, building blocks, and final compounds from milligrams to multi-kilograms.
Library Synthesis
At Alentris Synthesis, we specialize in designing, executing, and delivering compound libraries tailored to client needs. Our in-house technical expertise enables the efficient creation of both general and focused libraries, ensuring high-quality results. We consistently achieve over 70% compound delivery success rates and greater than 90% compound purity.